Nucleotide Excision Repair in Eukrayotes

用法例句

DNA repair mechanisms include nucleotide excision repair,mismatch repair and base exision repair which all associate with cisplatin resistance,and nucleotide excision repair is the main mechanism responsible for it.

目前研究发现,DNA修复途径中的核苷酸切除修复、错配修复、碱基切除修复均与顺铂耐药有关,核苷酸切除修复为其中最为重要的途径。

BACKGROUND &OBJECTIVE:Nucleotide excision repair is an important pathway for cellular DNA d amag e repair.

背景与目的:核苷酸切除修复机制是细胞修复损伤DNA的重要途径,肿瘤细胞的耐药常伴随DNA损伤修复基因表达增强,采取反义策略降低细胞的DNA损伤修复能力可以增加肿瘤细胞的药物敏感性。

Background &Objective:Nucleotide excision repair(NER)is a multi-enzyme DNA repair system i n eukaryotes.

背景与目的:核苷酸切除修复(Nucleotideexcisionrepair,NER)是真核细胞中的DNA修复多酶系统,它可能与人肿瘤细胞对抗癌药的耐药有关。

BACKGROUND & OBJECTIVE:Previous studies using glioma cell lines demonstrated that the expression of ERCC2, a important factor in nucleotide excision repair(NER) system, is associated with chemoresistance of carmustine(BCNU).

背景与目的:以往细胞株的研究提示,核苷酸切除修复系统中的重要因子ERCC2表达与BCNU耐药相关,然而在人脑胶质瘤是否同样如此,还没有明确资料。

XPC and XPD gene are Nucleotide Excision Repair (NER) genes.

核苷酸切除修复为DNA修复途径之一,且核苷酸切除修复基因具有高度多态性。

Objective] To assess the possible association between the expression levels of nucleotide excision repair genes with lung cancer susceptibility.

[目的 ]探讨核苷酸切除修复基因表达水平与肺癌易感性关系。

Significance of ERCC1 Expression in Lung Cancer

核苷酸切除修复基因ERCC1在肺癌中表达的意义

Nucleotide Excision Repair in DNA Damage of Human Embryonic Kidney 293 Cells Induced by Nephrotoxicant;

肾脏毒物致人胚肾293细胞DNA损伤的核苷酸切除修复

The Association of Expression Levels of Nucleotide Excision Repair Genes with Lung Cancer Susceptibility;

核苷酸切除修复基因表达水平与肺癌易感性关系的研究

The Investigation of Correlation of Genetic Polymorphisms in Nucleotide Excision Repair System to Platinum Drug Sensitivity of Epithelial Ovarian Cancer

核苷酸切除修复基因多态性与卵巢癌铂类药物耐药相关性研究

Nucleotide excision repair genetic polymorphisms and resistance of platinum

核苷酸切除修复基因多态性和铂类药物耐药性关系研究进展

Correlation of Nucleotide Excision Repair Gene XPC and XPD Polymorphisms to Esophageal Squamous Cell Carcinoma and Gastric Cardiac Adenocarcinoma;

核苷酸切除修复基因XPC、XPD单核苷酸多态性与食管癌、贲门癌的关联研究

Association between the Nucleotide Excision Repair (NER) Genes Polymorphisms and Genetic Susceptibility and Clinical Phenotype of Hepatocellular Carcinoma;

核苷酸切除修复基因多态性与肝癌遗传易感性及临床表型的关联研究

The Associations of Genetic Variations in Nucleotide Excision Repair Genes with DNA Damage in Coke-oven Workers and Lung Cancer Risk

核苷酸切除修复基因多态性与焦炉工DNA损伤及肺癌易感性的关联研究

Relationship between polymorphisms of DNA repair genes and glutathione-S-transferase genes and risk of biliary tract cancer

核苷酸切除修复基因和谷胱甘肽-S-转移酶基因多态与胆道癌风险关系的研究

Association between nucleotide excision repair gene polymorphisms and chromosomal damage in coke-oven workers;

焦炉作业工人核苷酸剪切修复酶基因多态性与染色体损伤的关系

The Effect of TGF-β_2 ASON to the Repair of Injury Rabbit Cornea;

TGF-β_2反义寡核苷酸对兔角膜损伤修复的影响

Amino Acid Substitution Polymorphisms of the DNA Repair Gene XRCC1/MGMT and the Susceptibility to Cervical Carcinoma;

DNA修复基因XRCC1和MGMT单核苷酸多态性与宫颈癌易感性的关系

The Correlation of DNA Repair Gene XPD Polymorphisms to Ovarian Cancer;

DNA修复基因XPD单核苷酸多态性与卵巢癌的关联研究

Association of Genetic Polymorphisms of the DNA Repair Gene XPD with the Risk of Arsenism;

DNA修复基因XPD单核苷酸多态性与地方性砷中毒关系的研究

Association of Genetic Polymorphisms in the DNA Repair Gene XPA and Risk of Lung Cancer;

DNA修复基因XPA单核苷酸多态性与肺癌遗传易感性的研究

Single Nucleotide Polymorphisms in DNA Repair and Carcinogen-Metabolizing Genes and Susceptibility to Bladder Cancer

DNA修复基因和毒物代谢基因单核苷酸多态与膀胱癌遗传易感性

Polymorphisms of DNA Repair Gene XRCC4 and Susceptibility to Gastric Cancer in Chinese People

修复基因XRCC4单核苷酸多态性与胃癌易感关联性的研究

The Study on DNA Repair Genes Polymorphisms and Susceptibility to Non-Hodgkin's Lymphoma

DNA修复基因单核苷酸多态性与非霍奇金淋巴瘤遗传易感性的研究